Tauro 6-ethlchenodeoxycholic acid-d5(sodium）

Tauro 6-ethlchenodeoxycholic acid-d5(sodium）

• UNSPSC Description: Tauro 6-ethlchenodeoxycholic acid-d5(sodium） is deuterium labeled Tauro-obeticholic acid. Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1][2].
• Target Antigen: FXR; Isotope-Labeled Compounds
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Inflammation/Immunology
• Smiles: OC1CC[C@]2([C@@]([H])(C1)[C@H]([C@H]([C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)[H])[H])C)[H])[H])O)C([2H])(C([2H])([2H])[2H])[2H])C
• Molecular Weight: 554.77
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported