LDV

• Description :

  LDV is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells[1][2].

• UNSPSC :

  12352209

• Target :

  Integrin

• Type :

  Peptides

• Related Pathways :

  Cytoskeleton

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ldv.html

• Purity :

  99.27

• Solubility :

  DMSO : ≥ 12.5 mg/mL

• Smiles :

  NCCCC[C@@H](C(O)=O)NC([C@H](C)NC([C@H](C)NC([C@H]1N(C([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)=O)=O)=O)=O)CCC1)=O)=O)=O

• Molecular Formula :

  C48H70N10O12

• Molecular Weight :

  979.13

• References & Citations :

  [1]Ben H Njus, et al. Conformational mAb as a tool for integrin ligand discovery. Assay Drug Dev Technol. 2009 Oct;7 (5) :507-15.|[2]Estelle Gérard, et al. LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :586-90.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Scientific Category :

  Peptides

• Clinical Information :

  Phase 4

• CAS Number :

  [1155866-55-9]