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MS47134

CAT: 0804-HY-148244-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148244-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS47134 is a potent and selective MRGPRX4 agonist with an EC50 value of 149 nM. MS47134 can be used for research of pain, itch and mast cell-mediated hypersensitivity[1].
UNSPSC
12352005
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ms47134.html
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@]12C[C@@H](C[C@@]3(C)C2)C[C@](C3)(C)C1)N[C@@H](C(O)=O)CC4=CC=CC=C4
Molecular Formula
C22H29NO3
Molecular Weight
355.47
References & Citations
[1]Cao C, et al. Structure, function and pharmacology of human itch GPCRs. Nature. 2021 Dec;600 (7887) :170-175.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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