Propargyl-PEG4-CH2CH2-Boc

Propargyl-PEG4-CH2CH2-Boc

• CAS Number: 1245823-50-0
• UNSPSC Description: Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: ADC Linker; PROTAC Linkers
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/propargyl-peg4-ch2ch2-boc.html
• Purity: 97.0
• Solubility: 10 mM in DMSO
• Smiles: C#CCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O
• Molecular Weight: 360.44
• References & Citations: [1]Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported