Propargyl-PEG8-NH2
CAT:
804-HY-130182-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propargyl-PEG8-NH2
- CAS Number: 1196732-52-1
- UNSPSC Description: Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: ADC Linker; PROTAC Linkers
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/propargyl-peg8-nh2.html
- Purity: 98.0
- Solubility: 10 mM in DMSO
- Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCN
- Molecular Weight: 407.50
- References & Citations: [1]Genady AR, et al. Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That TargetProstate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy. J Med Chem. 2016 Mar 24;59(6):2660-73.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported