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Galectin 3 Polyclonal Antibody

CAT: 0763-D-AB-10120L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10120L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell, being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation, apoptosis, angiogenesis, immune response, neoplastic transformation and metastasis .
Abbreviation
Galectin
UniProt
P17931
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant Human LGALS3 protein expressed by E.coli
Target
35 kDa lectin; Carbohydrate binding protein 35; Carbohydrate-binding protein 35; CBP 35; CBP35; Gal-3; GAL3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin 3 internal gene; included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-31; L-34 galactoside-binding lectin; L31; Laminin-binding protein; Lectin L-29; Lectin; galactose binding; soluble 3; LEG3; LGALS2; LGALS3; MAC 2 antigen; Mac-2; Mac-2 antigen; MAC2; Macrophage galactose-specific lectin; MGC105387
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells; Cancer
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:150-1:300
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
26 kDa
Isotype
IgG

UniProtKB · P17931

Galectin-3

LEG3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17931
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LGALS3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Gal-3
EC number
—
Processing
—
Secondary accessions
B2RC38, Q16005, Q6IBA7, Q96J47
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondPhosphoprotein

Cellular component

CytoplasmNucleusSecretedSpliceosome

Biological process

DifferentiationImmunityInnate immunitymRNA processingmRNA splicing

Molecular function

IgE-binding protein

Ligand

Lectin

Domain

Repeat
Product Datasheet
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