Anti-Reticulon-4 receptor-like 1 RTN4RL1 Antibody

• Description:

  Boster Bio Anti-Reticulon-4 receptor-like 1 RTN4RL1 Antibody catalog # A12234. Tested in WB applications. This antibody reacts with Mouse, Rat.

• Synonyms:

  Reticulon-4 receptor-like 1; Nogo receptor-like 2; Nogo-66 receptor homolog 2

• Gene Name:

  RTN4RL1

• UniProt:

  Q86UN2

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human RTN4RL1 (NP_848663.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:1000-1:4000

• Form:

  Liquid

• Function:

  Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity) . Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200) . Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200) .

• Molecular Weight:

  49065 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Reticulon-4 receptor-like 1

• Subcellular Location:

  Cell membrane

• Protein Name:

  Reticulon-4 receptor-like 1