Anti-Proteasome subunit beta type-7 PSMB7 Antibody

• Description:

  Boster Bio Anti-Proteasome subunit beta type-7 PSMB7 Antibody catalog # A08095. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Proteasome subunit beta type-7;3.4.25.1

• Gene Name:

  PSMB7

• UniProt:

  Q99436

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PSMB7 (NP_002790.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.

• Applications:

  WB, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) . Within the 20S core complex, PSMB7 displays a trypsin-like activity.

• Molecular Weight:

  29965 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Proteasome subunit beta type-7

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Proteasome subunit beta type-7