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Anti-EDF1 Antibody

CAT: 0519-A07668Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07668Size:100 µL
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Description
Boster Bio Anti-EDF1 Antibody catalog # A07668. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Endothelial differentiation-related factor 1; EDF-1; Multiprotein-bridging factor 1; MBF1; EDF1;
Gene Name
EDF1
UniProt
O60869
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human EDF1 (NP_003783.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in brain, liver, lung, kidney and heart (at protein level) . Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Molecular Weight
16369 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Endothelial differentiation-related factor 1
Subcellular Location
Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Protein Name
Endothelial differentiation-related factor 1

UniProtKB · O60869

Endothelial differentiation-related factor 1

EDF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60869
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EDF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
EDF-1
EC number
—
Processing
—
Secondary accessions
Q5T5T2, Q9UIM1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Molecular function

ActivatorCalmodulin-bindingDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

DifferentiationTranscriptionTranscription regulation

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