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Anti-DTX2 Antibody

CAT: 0519-A07222Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07222Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-DTX2 Antibody catalog # A07222. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Probable E3 ubiquitin-protein ligase DTX2;2.3.2.27
Gene Name
DTX2
UniProt
Q86UW9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human DTX2.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Molecular Weight
67246 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Probable E3 ubiquitin-protein ligase DTX2
Subcellular Location
Cytoplasm
Protein Name
Probable E3 ubiquitin-protein ligase DTX2

UniProtKB · Q86UW9

Probable E3 ubiquitin-protein ligase DTX2

DTX2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86UW9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DTX2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
Q4ZH49, Q6XM87, Q6XM88, Q96H69, Q9H890, Q9P200
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeCytoplasmNucleus

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathwayUbl conjugation pathway

Domain

RepeatZinc-finger

Molecular function

Transferase

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