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Anti-SLC27A2 Antibody

CAT: 0519-A07140Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07140Size:100 µL
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Description
Boster Bio Anti-SLC27A2 Antibody catalog # A07140. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Very long-chain acyl-CoA synthetase; VLACS; VLCS;6.2.1.-; Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase;6.2.1.3; Solute carrier family 27 member 2; THCA-CoA ligase; Very long-chain-fatty-acid-CoA ligase; SLC27A2; ACSVL1, FACVL1, FATP2, VLACS;
Gene Name
SLC27A2
UniProt
O14975
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human FATP2 (NP_003636.2) .
Clonality
Polyclonal
Tissue Specificity
Expressed in liver, kidney, placenta and pancreas.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precursors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity) .
Molecular Weight
70312 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Very long-chain acyl-CoA synthetase
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Peripheral membrane associated with the lumenal side of peroxisomes.
Protein Name
Very long-chain acyl-CoA synthetase

UniProtKB · O14975

Long-chain fatty acid transport protein 2

S27A2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14975
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC27A2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K2J7, Q53FY6, Q6PF09
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumMembraneMicrosomePeroxisome

Biological process

Fatty acid metabolismLipid metabolismLipid transportTransport

Molecular function

Ligase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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