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Anti-WDR11 Antibody

CAT: 0519-A06920Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06920Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-WDR11 Antibody catalog # A06920. Tested in WB applications. This antibody reacts with Human.
Synonyms
WD repeat-containing protein 11; Bromodomain and WD repeat-containing protein 2; WD repeat-containing protein 15; WDR11; BRWD2, KIAA1351, WDR15;
Gene Name
WDR11
UniProt
Q9BZH6
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human WDR11 (NP_060587.8) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:1000-1:2000
Form
Liquid
Function
Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200) . Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200) . WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1) -derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin- mediated capture of vesicles generated using AP-1 (PubMed:29426865) .
Molecular Weight
136685 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
WD repeat-containing protein 11
Subcellular Location
Cytoplasm, cytoskeleton, cilium basal body
Protein Name
WD repeat-containing protein 11

UniProtKB · Q9BZH6

WD repeat-containing protein 11

WDR11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BZH6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WDR11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5VWA1, Q9P2J6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell projectionCytoplasmCytoplasmic vesicleCytoskeletonGolgi apparatusNucleus

Coding sequence diversity

Chromosomal rearrangement

Disease

Disease variantHypogonadotropic hypogonadismIntellectual disabilityKallmann syndromeProto-oncogene

PTM

Phosphoprotein

Domain

RepeatWD repeat

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