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Anti-PLOD3 Antibody

CAT: 0519-A06773Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06773Size:100 µL
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Description
Boster Bio Anti-PLOD3 Antibody catalog # A06773. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3;1.14.11.4
Gene Name
PLOD3
UniProt
O60568
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PLOD3 (NP_001075.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous (PubMed:9724729) . Detected in heart, placenta and pancreas, and at lower levels in lung, liver and skeletal muscle (PubMed:9582318, PubMed:9724729) .
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen (PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968) . Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys- Gly- sequences in collagens (PubMed:9582318, PubMed:9724729, PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968) . Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968) . Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:10934207, PubMed:11896059, PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968) . Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660) . Essential for normal biosynthesis and secretion of type IV collagens (PubMed:18834968) (Probable) . Essential for normal formation of basement membranes (By similarity) .
Molecular Weight
84785 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
Subcellular Location
Rough endoplasmic reticulum
Protein Name
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

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