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Anti-SIN3B Antibody

CAT: 0519-A06424-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06424-1Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-SIN3B Antibody catalog # A06424-1. Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Synonyms
Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b; SIN3B
Gene Name
SIN3B
UniProt
O75182
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.
Clonality
Polyclonal
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Molecular Weight
133066 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Paired amphipathic helix protein Sin3b
Subcellular Location
Nucleus
Protein Name
Paired amphipathic helix protein Sin3b

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