Anti-ERC1 Antibody

• Description :

  Boster Bio Anti-ERC1 Antibody catalog # A05640. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms :

  ELKS/Rab6-interacting/CAST family member 1; ERC-1; Rab6-interacting protein 2; ERC1; ELKS, KIAA1081, RAB6IP2;

• Gene Name :

  ERC1

• UniProt :

  Q8IUD2

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human ERC1 (NP_829884.1) .

• Clonality :

  Polyclonal

• Tissue Specificity :

  Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested.

• Applications :

  WB

• Purification :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution :

  WB: 1:500-1:2000

• Form :

  Liquid

• Function :

  Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.

• Molecular Weight :

  128086 MW

• Shipping Conditions :

  Available

• Storage Conditions :

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names :

  ELKS/Rab6-interacting/CAST family member 1

• Subcellular Location :

  Cytoplasm . Membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein . In neurons, localized closed to presynaptic membrane. Recruited on Golgi membranes by RAB6A in a GTP-dependent manner (By similarity) . .

• Protein Name :

  ELKS/Rab6-interacting/CAST family member 1