Anti-Neuroglobin NGB Antibody

• Description:

  Boster Bio Anti-Neuroglobin NGB Antibody catalog # A05551. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Neuroglobin; NGB;

• Gene Name:

  NGB

• UniProt:

  Q9NPG2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human NGB (NP_067080.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus.

• Applications:

  WB, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

• Molecular Weight:

  16933 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Neuroglobin

• Subcellular Location:

  Perikaryon . Cytoplasm. Mitochondrion.

• Protein Name:

  Neuroglobin