Anti-MARK3 Antibody

• Description:

  Boster Bio Anti-MARK3 Antibody catalog # A05355-1. Tested in WB, IP, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  MAP/microtubule affinity-regulating kinase 3;2.7.11.1; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78; MARK3; CTAK1, EMK2;

• Gene Name:

  MARK3

• UniProt:

  P27448

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human Mark3 aa 600-750.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitous.

• Applications:

  WB, IP, ICC, IF, IHC, Flow Cytometry

• Purification:

  Protein A purified.

• Form:

  Liquid

• Function:

  Serine/threonine-protein kinase (PubMed:23666762) . Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule- associated protein MAPT/TAU (PubMed:23666762) . Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613) . Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714) .

• Molecular Weight:

  84429 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  MAP/microtubule affinity-regulating kinase 3

• Subcellular Location:

  Cell membrane

• Protein Name:

  MAP/microtubule affinity-regulating kinase 3