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Anti-MAP3K4 Antibody

CAT: 0519-A04842-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A04842-1Size:100 µL
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Description
Boster Bio Anti-MAP3K4 Antibody catalog # A04842-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Mitogen-activated protein kinase kinase kinase 4;2.7.11.25; MAP three kinase 1; MAPK/ERK kinase kinase 4; MEK kinase 4; MEKK 4; MAP3K4; KIAA0213, MAPKKK4, MEKK4, MTK1;
Gene Name
MAP3K4
UniProt
Q9Y6R4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human MAP3K4.
Clonality
Polyclonal
Tissue Specificity
Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
Molecular Weight
181685 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Mitogen-activated protein kinase kinase kinase 4
Subcellular Location
Cytoplasm, perinuclear region . Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles. .
Protein Name
Mitogen-activated protein kinase kinase kinase 4

UniProtKB · Q9Y6R4

Mitogen-activated protein kinase kinase kinase 4

M3K4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6R4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP3K4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.25
Processing
—
Secondary accessions
A6H8W0, B7ZLD3, B9EG75, Q5VTT8, Q5VTT9, Q92612, Q9H408
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cytoplasm

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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