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Anti-PRMT2 Antibody

CAT: 0519-A04706Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A04706Size:100 µL
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Description
Boster Bio Anti-PRMT2 Antibody catalog # A04706. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Protein arginine N-methyltransferase 2;2.1.1.319
Gene Name
PRMT2
UniProt
P55345
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human PRMT2.
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR) -mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER) -mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1- dependent manner) . May be involved in growth regulation.
Molecular Weight
49042 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Protein arginine N-methyltransferase 2
Subcellular Location
Isoform 1: Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure. Excluded from nucleolus.
Protein Name
Protein arginine N-methyltransferase 2