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Anti-HAND2 Antibody

CAT: 0519-A04652Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A04652Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-HAND2 Antibody catalog # A04652. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Heart- and neural crest derivatives-expressed protein 2; Class A basic helix-loop-helix protein 26; bHLHa26; Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2; dHAND; HAND2; BHLHA26, DHAND;
Gene Name
HAND2
UniProt
P61296
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HAND2 (NP_068808.1) .
Clonality
Polyclonal
Tissue Specificity
Heart.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity) . .
Molecular Weight
23666 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Heart- and neural crest derivatives-expressed protein 2
Subcellular Location
Nucleus
Protein Name
Heart- and neural crest derivatives-expressed protein 2

UniProtKB · P61296

Heart- and neural crest derivatives-expressed protein 2

HAND2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61296
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HAND2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B6ECG9, O95300, O95301, P97833, Q494T1
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisDifferentiationTranscriptionTranscription regulation

Molecular function

Developmental proteinDNA-binding

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

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AZP57102-FITCAnti-Zebrafish HAND2 Antibody FITC Conjugated
AZP57102-BiotinAnti-Zebrafish HAND2 Antibody Biotin Conjugated
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STJ501311Anti-HAND2 Antibody BIOTIN
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