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Anti-Histone acetyltransferase KAT7 KAT7 Antibody

CAT: 0519-A03896-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A03896-1Size:100 µL
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Description
Boster Bio Anti-Histone acetyltransferase KAT7 KAT7 Antibody catalog # A03896-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Histone acetyltransferase KAT7;2.3.1.48
Gene Name
KAT7
UniProt
O95251
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed, with highest levels in testis.
Applications
WB, IHC, IP
Purification
ProA affinity purified
Form
Liquid
Function
Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity) . Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067) . Specifically represses AR-mediated transcription.
Molecular Weight
70642 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Histone acetyltransferase KAT7
Subcellular Location
Nucleus, nucleoplasm
Protein Name
Histone acetyltransferase KAT7

UniProtKB · O95251

Histone acetyltransferase KAT7

KAT7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95251
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KAT7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.48
Processing
—
Secondary accessions
B3KN74, B4DF85, B4DFB4, B4DFE0, B4DGY4, E7ER15, G5E9K7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

AcyltransferaseChromatin regulatorTransferase

Coding sequence diversity

Alternative splicing

Cellular component

CentromereChromosomeCytoplasmNucleus

Biological process

DNA damageDNA repairDNA replicationTranscriptionTranscription regulation

Ligand

Metal-bindingZinc

Domain

Zinc-finger

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