Anti-Glutamine synthetase GLUL Antibody

• Description:

  Boster Bio Anti-Glutamine synthetase GLUL Antibody catalog # A03191-2. Tested in WB, IHC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Glutamine synthetase

• Gene Name:

  GLUL

• UniProt:

  P15104

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Glutamine Synthetase.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in endothelial cells.

• Applications:

  WB, IHC, IP, Flow Cytometry

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed:30158707, PubMed:16267323) . Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity) . Essential for proliferation of fetal skin fibroblasts (PubMed:18662667) . Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (PubMed:30158707) . May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (PubMed:30158707) .

• Molecular Weight:

  42064 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Glutamine synthetase

• Subcellular Location:

  Cytoplasm, cytosol

• Protein Name:

  Glutamine synthetase