Anti-Ataxin-7 ATXN7 Antibody

• Description:

  Boster Bio Anti-Ataxin-7 ATXN7 Antibody catalog # A02936. Tested in WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  Ataxin-7; Spinocerebellar ataxia type 7 protein; ATXN7; SCA7;

• Gene Name:

  ATXN7

• UniProt:

  O15265

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide corresponding to residues in Human ATXN7.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:1000

• Form:

  Liquid

• Function:

  Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization.

• Molecular Weight:

  95451 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Ataxin-7

• Subcellular Location:

  Isoform a: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.

• Protein Name:

  Ataxin-7