Anti-GluR2 GRIA2 Antibody

• Description:

  Boster Bio Anti-GluR2 GRIA2 Antibody catalog # A02905. Tested in WB, ICC, IF, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2; GRIA2; GLUR2;

• Gene Name:

  GRIA2

• UniProt:

  P42262

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein

• Clonality:

  Polyclonal

• Applications:

  WB, ICC, IF, IHC, IP

• Purification:

  ProA affinity purified

• Form:

  Liquid

• Function:

  Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity) .

• Molecular Weight:

  98821 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Glutamate receptor 2

• Subcellular Location:

  Cell membrane

• Protein Name:

  Glutamate receptor 2