Anti-CD207 Antibody

• Description:

  Boster Bio Anti-CD207 Antibody catalog # A02316-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  C-type lectin domain family 4 member K; Langerin; CD207; CD207; CLEC4K;

• Gene Name:

  CD207

• UniProt:

  Q9UJ71

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human Langerin/CD207 (NP_056532.4) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:2000

• Form:

  Liquid

• Function:

  Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs) ; is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

• Molecular Weight:

  36725 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  C-type lectin domain family 4 member K

• Subcellular Location:

  Membrane

• Protein Name:

  C-type lectin domain family 4 member K