Anti-CD40L CD40LG Antibody

• Description:

  Boster Bio Anti-CD40L CD40LG Antibody catalog # A01114. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse.

• Synonyms:

  CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40LG; CD40L, TNFSF5, TRAP;

• Gene Name:

  CD40LG

• UniProt:

  P29965

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein

• Clonality:

  Polyclonal

• Tissue Specificity:

  Specifically expressed on activated CD4+ T- lymphocytes.

• Applications:

  WB, ICC, IF, IHC, Flow Cytometry

• Purification:

  ProA affinity purified

• Form:

  Liquid

• Function:

  Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226) . Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933) . Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T- cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037) . Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity) .

• Molecular Weight:

  29274 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  CD40 ligand

• Subcellular Location:

  Cell membrane

• Protein Name:

  CD40 ligand