Anti-Polycomb protein SUZ12 SUZ12 Antibody

• Description:

  Boster Bio Anti-Polycomb protein SUZ12 SUZ12 Antibody catalog # A00583-3. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog; SUZ12; CHET9, JJAZ1, KIAA0160;

• Gene Name:

  SUZ12

• UniProt:

  Q15022

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein

• Clonality:

  Polyclonal

• Tissue Specificity:

  Overexpressed in breast and colon cancer.

• Applications:

  WB, ICC, IF, IP

• Purification:

  ProA affinity purified

• Form:

  Liquid

• Function:

  Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

• Molecular Weight:

  83055 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Polycomb protein SUZ12

• Subcellular Location:

  Nucleus

• Protein Name:

  Polycomb protein SUZ12