Anti-Caspase 9 (E119) CASP9 Antibody

• Description:

  Boster Bio Anti-Caspase 9 (E119) CASP9 Antibody catalog # A00080-2. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Caspase-9; CASP-9;3.4.22.62

• Gene Name:

  CASP9

• UniProt:

  P55211

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids 100-150 of Human Caspase 9.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

• Applications:

  WB, IHC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP) .

• Molecular Weight:

  46281 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Caspase-9

• Protein Name:

  Caspase-9