Human MEP1A ELISA Kit PicoKine®

Human MEP1A ELISA Kit PicoKine®

• Background: Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that in humans is encoded by the MEP1A gene. Meprin A subunit alpha, encoded by the **MEP1A** gene, is a component of the meprin A metalloproteinase complex, which is involved in extracellular matrix remodeling and proteolysis. Meprin A is a zinc-dependent endopeptidase found predominantly in the kidneys, intestines, and other tissues. It plays a crucial role in various physiological processes, including inflammation, tissue repair, and the processing of bioactive peptides. The alpha subunit, specifically, is a part of the hetero-oligomeric enzyme complex, which combines with the beta subunit to form an active enzyme. Abnormalities in meprin A function have been associated with several pathological conditions, including kidney diseases and cancer.
• Description: Human MEP1A ELISA Kit PicoKine® (96 Tests). Quantitate Human MEP1A in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Gene Name: MEP1A
• Gene ID: 4224
• UniProt: Q16819
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: V22-Q601
• Applications: ELISA
• Sample Type: cell culture supernatants, serum and plasma (heparin, EDTA).
• Detection Range: 1.56 ng/ml - 100 ng/ml
• Sensitivity: <50 pg/ml
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	2306	2413	2894	2515	2532	97.23	3.8%
  Sample 2	10121	8303	10346	10403	9793	553.32	5.7%
  Sample 3	43453	33164	27466	33589	34418	2725.91	7.9%

  *number of samples for each test n=16.
• : heparin or EDTA