Anti-Semaphorin 3B/SEMA3B Antibody Picoband®, Biotine Conjugate

Anti-Semaphorin 3B/SEMA3B Antibody Picoband®, Biotine Conjugate

• Background: Semaphorin-3B is a protein that in humans is encoded by the SEMA3B gene. It is mapped to 3p21.31. The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.
• Description: Boster Bio Anti-Semaphorin 3B/SEMA3B Antibody Picoband® catalog # A06559-1. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
• Synonyms: Semaphorin-3B; Sema A (V); Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA
• Gene Name: semaphorin 3B
• Gene ID: 7869
• UniProt: Q13214
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Cross Reactivity: No cross-reactivity with other proteins.
• Immunogen: E.coli-derived human Semaphorin 3B/SEMA3B recombinant protein (Position: Y55-R624).
• Clonality: Polyclonal
• Applications: ELISA,IF,IHC,ICC,WB
• Purification: Immunogen affinity purified.
• Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
• Form: Lyophilized
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
• Function: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
• References & Citations: 1. Ochi K, Mori T, Toyama Y, Nakamura Y, Arakawa H (2002). "Identification of semaphorin3B as a target of p53". Neoplasia. 4 (1): 82–7. 2. Tse C, Xiang RH, Bracht T, Naylor SL (January 2002). "Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line". Cancer Research. 62 (2): 542–6.
• Storage Conditions: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 104553 MW
• Observed Molecular Weight: 83 kDa
• Fragment: Rabbit IgG
• Specificity: No cross reactivity with other proteins.
• Applications Notes: Western blot, 0.1-0.5μg/ml
  Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
  Immunocytochemistry/Immunofluorescence, 2μg/ml
  ELISA, 0.1-0.5μg/ml