Human Interferon Lambda-1, IFNL1 Primacu™ ELISA Kit

Human Interferon Lambda-1, IFNL1 Primacu™ ELISA Kit

• Background: Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by a viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
• Description: Interferon lambda-1
• Synonyms: IL29;ZCYTO21
• Gene Name: IFNL1
• Gene ID: 282618
• UniProt: Q8IU54
• Origin Species: Human
• Reactivity: Human
• Target: IL-29
• Field of Research: Immunology
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 4.5 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 7.03-450 pg/mL
• Sensitivity: 1.4 pg/mL
• Weight: 21898
• Storage Temperature: 2-8°C