Human Activin receptor-like kinase 1, ACVRL1 Primacu™ ELISA Kit

Human Activin receptor-like kinase 1, ACVRL1 Primacu™ ELISA Kit

• Background: Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.
• Description: Serine/threonine-protein kinase receptor R3
• Synonyms: ACVRLK1;ALK1
• Gene Name: ACVRL1
• Gene ID: 94
• UniProt: P37023
• Origin Species: Human
• Reactivity: Human
• Target: ALK-1
• Field of Research: Cardiovascular,Metabolism,Signal transduction
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 10 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 15.63-1000 pg/mL
• Sensitivity: 3.62 pg/mL
• Weight: 56124
• Storage Temperature: 2-8°C