Human Kallikrein-13, KLK13 Primacu™ ELISA Kit

Human Kallikrein-13, KLK13 Primacu™ ELISA Kit

• Background: Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers and is regarded as a novel cancer biomarker. Besides, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.
• Description: Kallikrein-13
• Synonyms: KLKL4
• Gene Name: KLK13
• Gene ID: 26085
• UniProt: Q9UKR3
• Origin Species: Human
• Reactivity: Human
• Target: Kallikrein 13
• Field of Research: Cancer,Cell biology,Signal transduction
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 25 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 39.06-2500 pg/mL
• Sensitivity: 10.79 pg/mL
• Weight: 30570
• Storage Temperature: 2-8°C