Human Platelet Endothelial Cell Adhesion Molecule, PECAM1 Primacu™ ELISA Kit

Human Platelet Endothelial Cell Adhesion Molecule, PECAM1 Primacu™ ELISA Kit

• Background: The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
• Description: Platelet endothelial cell adhesion molecule
• Gene Name: PECAM1
• Gene ID: 5175
• UniProt: P16284
• Origin Species: Human
• Reactivity: Human
• Target: CD31
• Field of Research: Immunology,Cancer,Cardiovascular,Signal transduction,Stem cells
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 120 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 18.75-12000 pg/mL
• Sensitivity: 8.15 pg/mL
• Weight: 82522
• Storage Temperature: 2-8°C