Human Polymeric Immunoglobulin Receptor, PIGR Primacu™ ELISA Kit

Human Polymeric Immunoglobulin Receptor, PIGR Primacu™ ELISA Kit

• Background: Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
• Description: Polymeric immunoglobulin receptor
• Gene Name: PIGR
• Gene ID: 5284
• UniProt: P01833
• Origin Species: Human
• Reactivity: Human
• Target: PIGR
• Field of Research: Immunology
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 100 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 156.25-10000 pg/mL
• Sensitivity: 63.78 pg/mL
• Weight: 83284
• Storage Temperature: 2-8°C