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TH152

CAT: 0804-HY-168347Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168347Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TH152 is a reversible, pan ligand for LC3/GABARAP with a KD of 2 µM. LC3/GABARAP is an autophagy associated protein[1].
CAS Number
1622917-95-6
UNSPSC
12352005
Target
Atg8/LC3
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/th152.html
Smiles
OC(C1=CC=C(C=C1)C2=CSC(NC3=CC(Cl)=NC(SC(CCCCCC)C(O)=O)=N3)=N2)=O
Molecular Formula
C22H23ClN4O4S2
Molecular Weight
507.03
References & Citations
[1]Schwalm MP, et al., Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets. Nat Commun. 2024 Nov 25;15 (1) :10204.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T203365-01TH152

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