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(±) -Eriodictyol

CAT: 0804-HY-N0637A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0637A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -Eriodictyol ((±) -Huazhongilexone), a flavonoid, is a potent melanogenesis inhibitor with an IC50 of 48 μM. (±) -Eriodictyol suppresses tyrosinase, TRP-1, and TRP-2 mRNA expression. (±) -Eriodictyol has strong anti-plasmin activities[1].
CAS Number
4049-38-1
Product Name Alternative
(±) -Huazhongilexone; Dihydroluteolin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Melanocortin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/racemic-eriodictyol.html
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1CC(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C15H12O6
Molecular Weight
288.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Souichi Nakashima, et al. Inhibitors of melanogenesis in B16 melanoma 4A5 cells from flower buds of Lawsonia inermis (Henna) . Bioorg Med Chem Lett. 2015 Jul 1;25 (13) :2702-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

(+-)-Eriodictyol

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one is a member of flavanones.

CAS Number4049-38-1
PubChem CID11095
IUPAC Name2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
Molecular FormulaC15H12O6
Molecular Weight288.25
XLogP2
Topological Polar Surface Area107
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Heavy Atom Count21
Formal Charge0
Complexity400
SMILES
C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
InChI
InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2
InChIKey
SBHXYTNGIZCORC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (+-)-Eriodictyol
CAS: 4049-38-1
CID: 11095
Formula: C15H12O6
MW: 288.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight288.25
XLogP32
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass288.06338810
Monoisotopic Mass288.06338810
Topological Polar Surface Area107 Ų
Heavy Atom Count21
Formal Charge0
Complexity400
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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