7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid

• CAS Number: 89560-01-0
• UNSPSC Description: 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM)[1].
• Target Antigen: Phospholipase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/7-7-dimethyl-5z-8z-eicosadienoic-acid.html
• Smiles: CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(O)=O
• Molecular Weight: 336.55
• References & Citations: [1]Jannike M Andersen, et al. Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease. Neurochem Res. 2003 Feb;28(2):319-26.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported