ZT-1a
CAT:
804-HY-136532-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZT-1a
- CAS Number: 212135-62-1
- UNSPSC Description: ZT-1a is a potent, non-ATP-competitive and selective SPAK inhibitor. ZT-1a inhibits SPAK activity with IC50s of 44.3, 35.0, 46.7 μM at ATP concentrations of 0.01, 0.1 and 1 mM, respectively[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/zt-1a.html
- Smiles: O=C(NC1=CC(Cl)=C(C(C2=CC=C(Cl)C=C2)C#N)C=C1C)C3=CC(Cl)=CC=C3O
- Molecular Weight: 445.73
- References & Citations: [1]Jinwei Zhang, et al. Modulation of Brain cation-Cl- Cotransport via the SPAK Kinase Inhibitor ZT-1a. Nat Commun. 2020 Jan 7;11(1):78.
- Shipping Conditions: Room Temperature