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Alamandine

CAT: 0804-HY-P3108-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3108-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions[1][2].
CAS Number
1176306-10-7
UNSPSC
12352209
Target
Angiotensin Receptor; Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/alamandine.html
Purity
99.9
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
CC[C@H](C)[C@@H](C(N[C@@H](CC1=CN=CN1)C(N2CCC[C@H]2C(O)=O)=O)=O)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C)N)=O)=O)=O)=O
Molecular Formula
C40H62N12O9
Molecular Weight
855.00
References & Citations
[1]Daniel C Villela, et al. Alamandine: a new member of the angiotensin family. Curr Opin Nephrol Hypertens. 2014 Mar;23 (2) :130-4.|[2]Johanna Schleifenbaum. Alamandine and Its Receptor MrgD Pair Up to Join the Protective Arm of the Renin-Angiotensin System. Front Med (Lausanne) . 2019 Jun 11;6:107.|[3]Chi Liu, et al. Alamandine attenuates hypertension and cardiac hypertrophy in hypertensive rats. Amino Acids. 2018 Aug;50 (8) :1071-1081.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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