RB-3

CAT: 0804-HY-139514-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-139514-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to RING1B-BMI1f, with a Kd of 2.8 μM[1].

CAS Number

2396639-11-3

UNSPSC

12352005

Target

E1/E2/E3 Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rb-3.html

Purity

99.42

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C2=C3C=CNC3=CC=C2Cl)C(C(C)C)=C(C4=C5C=CNC5=CC=C4)N1)O

Molecular Formula

C24H20ClN3O2

Molecular Weight

417.89

References & Citations

[1]Shirish Shukla, et al. Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat Chem Biol. 2021 Jul;17 (7) :784-793.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-D2893D	RB-PEG-RB (MW 2000)
HY-D2893C	RB-PEG-RB (MW 3400)
HY-D2893A	RB-PEG-RB (MW 400)
HY-D2893M	RB-PEG-RB (MW 20000)
HY-D2893E	RB-PEG-RB (MW 4000)
HY-D2893	RB-PEG-RB (MW 600)
HY-D2893L	RB-PEG-RB (MW 10000)
HY-D2893K	RB-PEG-RB (MW 8000)
HY-D2893J	RB-PEG-RB (MW 6000)
HY-D2893H	RB-PEG-RB (MW 5000)

Alternative Products

Catalog	Name
GTR19259950-01	RB-3
1211987	Reagent: Boro3.3, RB, with
sc-377524	P-Rb (C-3)
P40015-100µL	Ab RB GluR2/3*
4260031	FLASKS RB 3 L
E8ET1607-9	Rb
T211749-01	RB-PEG-RB (MW 8000)
T211468-01	RB-PEG-RB (MW 2000)
FL045002-3.4K	RB-PEG-OH, 3.4K
FL045022-3.4K	RB-PEG-Mal, 3.4K

RB-3

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