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TWEAK Recombinant Protein

CAT: 0013-GTR18911642-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18911642-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TWEAK Recombinant Protein
Product Name Alternative
APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor necrosis factor ligand superfamily member 12, APO3 ligand
UniProt
O43508
Source
E. coli
Field of Research
Cell Biology
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Assay 1: The ED50 was determined by the dose - dependent stimulation of IL - 8 production by Human PBMC is less than 10 ng/mL.Assay 2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN - γ. The ED50 for this effect is between 30 - 45 ng/mL.
Form
Lyophilized
Storage Conditions
The lyophilized TWEAK recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TWEAK is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TWEAK recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_003800.1
AA Sequence
MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH

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