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PDGF-AB Recombinant Protein

CAT: 0013-GTR18909522-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18909522-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDGF-AB Recombinant Protein
Product Name Alternative
PDGF1, PDGF-A, PDGF1, Platelet-derived growth factor subunit A, PDGF-1, PDGF subunit A
UniProt
P04085
Source
E. coli
Field of Research
Cancer Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
The ED50 was determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 1 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Form
Lyophilized
Storage Conditions
The lyophilized PDGF-AB recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted PDGF-AB is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing PDGF-AB recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_002598.4
AA Sequence
Alpha Chain: SIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPTBeta Chain: SLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIGIVR KKPIFKKATV TLGDHLACKC ETVAAARPVT

UniProtKB · P04085

Platelet-derived growth factor subunit A

PDGFA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04085
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PDGFA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PDGF subunit A
EC number
—
Processing
Precursor
Secondary accessions
B5BU73
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Molecular function

Developmental proteinGrowth factorMitogen

Cellular component

Secreted

Domain

Signal

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