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Furin Recombinant Protein

CAT: 0013-GTR18909493-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18909493-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Furin Recombinant Protein
Product Name Alternative
FUR, PACE, SPC1, PCSK3, FUR, Furin, Dibasic-processing enzyme
UniProt
P09958
Source
High-5 Insect cells
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Biological activity was measured by its ability to cleave the fluorogenic peptide substrate Boc-Arg-Val-Arg-Arg-AMC (Bachem Catalog# I-1645.0025) . Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Form
Lyophilized
Storage Conditions
The lyophilized Furin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Furin stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Furin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_001276752.1
AA Sequence
DLNVKAAWAQ GYTGHGIVVS ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR IGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV WASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKC TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLD AGAMVALAQN WTTVAPQRKC IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGD LAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE IENTSEANNY GTLTKFTLVL YGTAPEGLPV PPESSGCKTL TSSQACVVCE EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASV CAPC

UniProtKB · P09958

Furin

FURIN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09958
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FURIN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.75
Processing
Precursor
Secondary accessions
Q14336, Q6LBS3, Q9UCZ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Autocatalytic cleavageCleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeGolgi apparatusMembraneSecreted

Molecular function

Heparin-bindingHydrolaseProteaseSerine protease

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix

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