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CD152 [CTLA-4] Recombinant Protein

CAT: 0013-GTR18908911Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18908911Size:100 µg
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Description
CD152 [CTLA-4] Recombinant Protein
Product Name Alternative
CTLA-4
UniProt
P60568
Tag
Fc Tag
Source
NS1 cells
Field of Research
Immunology & Inflammation
Purity
>98% (SDS-PAGE) . Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza) .
Bioactivity
Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.
Form
Lyophilized
Storage Conditions
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Notes
For research use only.
Applications Notes
This recombinant proteins is for research use only.
NCBI Accession Number
NP_033973
Preservative
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 1mg/ml in sterile water. Add 1X PBS to the desired protein concentration.
AA Sequence
The extracellular domain of mouse CD152 [CTLA-4] (aa 38-160) is fused to the N-terminus of the Fc region of mouse IgG2a.

UniProtKB · P60568

Interleukin-2

IL2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P60568
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-2
EC number
—
Processing
Precursor
Secondary accessions
P01585
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Chromosomal rearrangement

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoprotein

Disease

Proto-oncogene

Cellular component

Secreted

Domain

Signal

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