Products for Research Use Only

TPA Recombinant Protein

CAT: 0013-GTR18909960Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18909960Size:0.05 mg
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Description
TPA Recombinant Protein
Product Name Alternative
T-PA, TPA, t-plasminogen activator, Tissue plasminogen activator, PLAT
UniProt
P00750
Tag
C-6 His tag
Source
Human Cells
Field of Research
Cancer Biology, Cell Biology, Immunology & Inflammation, Metabolism Research
Purity
Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Form
Lyophilized
Molecular Weight
61.65 kD
Storage Conditions
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at -20°C for 3 months.
Notes
For research use only.
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Accession Number
P00750
Preservative
Lyophilized from a 0.2 um filtered solution of 20mM MES,150mM NaCl,0.2mM GaCl2, pH5.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
AA Sequence
Ser36-Pro562

UniProtKB · P00750

Tissue-type plasminogen activator

TPA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00750
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLAT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
t-PA, t-plasminogen activator, tPA
EC number
3.4.21.68
Processing
Precursor
Secondary accessions
A8K022, B2R8E8, Q15103, Q503B0, Q6PJA5, Q7Z7N2, Q86YK8, Q9BU99, Q9BZW1
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinZymogen

Domain

EGF-like domainKringleRepeatSignal

Molecular function

HydrolaseProteaseSerine protease

Biological process

Plasminogen activation

Cellular component

Secreted

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