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EGFR Recombinant Protein

CAT: 0013-GTR18907454Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18907454Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR Recombinant Protein
Product Name Alternative
Epidermal growth factor receptor, EGFR, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ErbB1, HER1
UniProt
P00533
Tag
C-6 His tag
Source
Human Cells
Field of Research
Cell Biology
Purity
Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Form
Lyophilized
Molecular Weight
39.7 kD
Storage Conditions
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at -20°C for 3 months.
Notes
For research use only.
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Accession Number
P00533
Preservative
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
AA Sequence
Leu25-Val30Gly&Asn298-Ser645

UniProtKB · P00533

Epidermal growth factor receptor

EGFR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00533
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EGFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Molecular function

Developmental proteinHost cell receptor for virus entryKinaseReceptorTransferaseTyrosine-protein kinase

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix

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