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Human FH protein

CAT: 0013-GTR18903361-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18903361-01Size:10 µg
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Description
Recombinant human FH protein is produced by our E. coli expression system and the target gene encoding Ala45-Lys510 is expressed.
Product Name Alternative
Fumarate hydratase mitochondrial; Fumarase
UniProt
P07954
Reactivity
Human
Source
E. coli
Field of Research
Cancer, DNA Damage, Epigenetics
Endotoxin
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Liquid
Storage Conditions
Store it at -20°C to -80°C for one year. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested Applications
ELISA, MS, SDS-PAGE, WB
Preservative
0.2 μM filtered solution of 20mM Tris, pH 8.0.
AA Sequence
MASQNSFRIE YDTFGELKVP NDKYYGAQTV RSTMNFKIGG VTERMPTPVI KAFGILKRAA AEVNQDYGLD PKIANAIMKA ADEVAEGKLN DHFPLVVWQT GSGTQTNMNV NEVISNRAIE MLGGELGSKI PVHPNDHVNK SQSSNDTFPT AMHIAAAIEV HEVLLPGLQK LHDALDAKSK EFAQIIKIGR THTQDAVPLT LGQEFSGYVQ QVKYAMTRIK AAMPRIYELA AGGTAVGTGL NTRIGFAEKV AAKVAALTGL PFVTAPNKFE ALAAHDALVE LSGAMNTTAC SLMKIANDIR FLGSGPRSGL GELILPENEP GSSIMPGKVN PTQCEAMTMV AAQVMGNHVA VTVGGSNGHF ELNVFKPMMI KNVLHSARLL GDASVSFTEN CVVGIQANTE RINKLMNESL MLVTALNPHI GYDKAAKIAK TAHKNGSTLK ETAIELGYLT AEQFDEWVKP KDMLGPK
Entrez
2271

UniProtKB · P07954

Fumarate hydratase, mitochondrial

FUMH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P07954
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Fumarase, HsFH
EC number
4.2.1.2
Processing
Precursor
Secondary accessions
B1ANK7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative initiation

Cellular component

ChromosomeCytoplasmMitochondrionNucleus

Disease

Disease variantTumor suppressor

Biological process

DNA damageDNA repairTricarboxylic acid cycle

Molecular function

Lyase

Domain

Transit peptide

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