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CD152 [CTLA-4] Recombinant Protein

CAT: 0013-GTR18908916Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18908916Size:500 µg
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Description
CD152 [CTLA-4] Recombinant Protein
Product Name Alternative
CTLA-4
UniProt
P01583
Tag
Fc Tag
Source
CHO cells
Field of Research
Immunology & Inflammation
Purity
>98% (SDS-PAGE) . Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza) .
Bioactivity
Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.
Form
Lyophilized
Storage Conditions
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Notes
For research use only.
Applications Notes
This recombinant proteins is for research use only.
NCBI Accession Number
NP_005205
Preservative
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 1mg/ml in sterile water. Add 1X PBS to the desired protein concentration.
AA Sequence
The extracellular domain of human CD152 [CTLA-4] (aa 37-160) is fused to the N-terminus of the Fc region of human IgG1.

UniProtKB · P01583

Interleukin-1 alpha

IL1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01583
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-1 alpha
EC number
—
Processing
Precursor
Secondary accessions
Q53QF9, Q7RU02
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinLipoproteinMyristatePhosphoprotein

Molecular function

CytokineMitogenPyrogen

Cellular component

CytoplasmNucleusSecreted

Biological process

Inflammatory response

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