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Glucagon peptide

CAT: 0013-GTR18896453-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18896453-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glucagon peptide
Source
Synthetic
Field of Research
Pharmacology & Drug Discovery
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
3482.78
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.
AA Sequence
His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr

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